Mastitis, inflammation of the mammary gland, is a costly disease as cows infected with it must be treated with antibiotics, and this means that until their infection fully clears, their milk cannot be produced and sold commercially. U.S. dairy producers lose more than $2 billion in production each year due to mastitis.
Specifically, the study data showed that "100% more udder-quarters from cows fed OxBC (oxidized beta carotene) underwent spontaneous resolution of bacterial infection compared to quarters from cows fed the control feed containing no antibiotics," the release noted. Resolution in the OxC-beta group was 13.9% versus 6.9% in the control group.
Also, only one udder-quarter in the OxC-beta group progressed from subclinical to full clinical mastitis compared to six in the control group.
"We have assessed a number of compounds in terms of their ability to help clear subclinical mastitis, and this is the first time we have seen a positive effect," said Scott McDougall in the release. He is the managing director of Cognosco, the veterinary services and research group that conducted the trial. Starting on September 19, 2019, it spanned 42 days and took place at four commercial dairy farms on New Zealand's North Island.
These new results, taken with those of an earlier study in China, "demonstrate the effectiveness of supporting immune function to help improve chronic conditions that affect health and reduce productivity in dairy cows," according to the release. "These two trials are building out a consistent performance and use case for OxC-beta Livestock across geographies and in this significant dairy cow market."
Accordingly, Avivagen filed for patent protection for the use of OxC-beta Livestock in the treatment of dairy cows.
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