MLV & Co. Disclosures:

Agenus Inc.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Agenus Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from Agenus Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Agenus Inc. in the next three months.

Peregrine Pharmaceuticals Inc:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Peregrine Pharmaceuticals Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from Peregrine Pharmaceuticals Inc. MLV or any affiliates in the past 12 months received compensation for products or services other than investment banking services from Peregrine Pharmaceuticals Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Peregrine Pharmaceuticals Inc. in the next three months.

ArQule Inc.:
MLV or any affiliates in the past 12 months received compensation for products or services other than investment banking services from ArQule Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from ArQule Inc. in the next three months.

Acadia Pharmaceuticals Inc.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Acadia Pharmaceuticals Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from Acadia Pharmaceuticals Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Acadia Pharmaceuticals Inc. in the next three months.

Keryx Pharmaceuticals Inc.:
MLV or any affiliates in the past 12 months received compensation for products or services other than investment banking services from Keryx Biopharmaceuticals Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Keryx Biopharmaceuticals Inc. in the next three months.

Threshold Pharmaceuticals:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Threshold Pharmaceuticals Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from Threshold Pharmaceuticals Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Threshold Pharmaceuticals Inc. in the next three months.

Dynavax technologies Corp.:
MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Dynavax Technologies Corp. in the next three months.

Genomic Health Inc.:
MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Genomic Health Inc. in the next three months.

Resverlogix Corp.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Resverlogix Corp. MLV or any affiliates in the past 12 months received compensation for investment banking services from Resverlogix Corp. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Resverlogix Corp. in the next three months.

Aastrom Biosciences Inc.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Aastrom Biosciences Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from Aastrom Biosciences Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Aastrom Biosciences Inc. in the next three months.

Prana Biotechnology Ltd.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for Prana Biotechnology Ltd. MLV or any affiliates in the past 12 months received compensation for investment banking services from Prana Biotechnology Ltd. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from Prana Biotechnology Ltd. in the next three months.

BioCryst Pharmaceuticals Inc.:
MLV or any affiliates in the past 12 months managed or co-managed a public offering of securities for BioCryst Pharmaceuticals Inc. MLV or any affiliates in the past 12 months received compensation for investment banking services from BioCryst Pharmaceuticals Inc. MLV or any affiliate expects to receive or intends to seek compensation for investment banking services from BioCryst Pharmaceuticals Inc. in the next three months.

Spectrum Pharmaceuticals Inc.
MLV or any affiliates expect to receive or intend to seek compensation for investment banking services from Spectrum Pharmaceuticals Inc. in the next three months. MLV or any affiliates in the past 12 months received compensation for products or services other than investment banking services from Spectrum Pharmaceuticals Inc.