Immunovaccine Inc.

Immunovaccine Inc. is a clinical stage biopharmaceutical company dedicated to making immunotherapy more effective, more broadly applicable, and more widely available to people facing cancer and other serious diseases. Immunovaccine develops T cell-activating cancer immunotherapies and other vaccine candidates based on DepoVax™, the company's patented platform that provides controlled and prolonged exposure of antigens and adjuvant to the immune system. Immunovaccine has advanced two T cell-activating therapies for cancer through Phase 1 human clinical trials and is currently conducting a Phase 1b study with Incyte Corporation assessing its lead cancer therapy, DPX-Survivac, as a combination therapy in ovarian cancer. The company is also exploring additional applications of DepoVax, including DPX-RSV, an innovative vaccine candidate for respiratory syncytial virus (RSV), which has recently completed a Phase 1 clinical trial. Immunovaccine also has ongoing clinical projects to assess the potential of DepoVax to address malaria and the Zika virus.

Expert Comments:

Echelon Wealth Partners analyst Doug Loe sees blue sky potential for one company's newly approved HIV compound, while the vaccine platform of a second company earned it Top Pick status as well.
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Douglas Loe, an analyst with Echelon Partners, outlined the reasons this biotech deserves Top Pick status.
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Douglas Loe, Echelon Wealth Partners (1/11/18)
"We continue to maintain Immunovaccine Inc. as our clinical development stage Top Pick for 2018. The company's profile as a cancer immune therapy developer was raised previously following a peer acquisition undertaken by California-based infectious disease drug development giant Gilead as it relates to the $11.9B acquisition of cancer immune therapy developer Kite. . .while the transaction does ascribe a substantial market valuation for a peer of Immunovaccine, we argue that there are thematic overlaps in the company on that basis."

André Uddin, Mackie Research Capital (12/7/17)
"Immunovaccine Inc. announced this morning that it was advancing DPX-NEO (a cancer vaccine) into a Phase 1 trial in conjunction with UConn Health. . .DPX-NEO should diversify the company's pipeline. . .we are maintaining our Speculative Buy rating and target price of $2.80."

This biotech reported positive results in a Phase 1b trial for its ovarian cancer immuno-oncology drug-delivery candidate, prompting increases in share price targets from a pair of analysts.
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Douglas Loe, Echelon Wealth Partners (12/5/17)
"Immunovaccine Inc. presented more interim data from its 40-patient, Phase 1/2, recurrent ovarian cancer trial, testing its lead lipid (DepoVax)-based, water-free, survivin-containing cancer immune therapy DPX-Survivac in combination with partner Incyte's IDO1 checkpoint inhibitor, small-molecule drug epacadostat. . .[it's] still early days for DPX-Survivac Phase 1/2 oncology activities, but encouraging signals that the immune therapy works as expected in ovarian cancer are already available."

André Uddin, Mackie Research Capital (12/5/17)
"We are increasing our target price to $2.80 from $2.20 previously, as Immunovaccine Inc. reported good results of a Phase 1b study testing the combined treatment of the company's DPX-Surivivac and Incyte's IDO1 inhibitor epacadostat in advanced ovarian cancer patients. . .of the ten ovarian cancer patients who completed the treatment with DPX-Survivac plus 100 mg epacadostat, three had partial responses and four had stable diseases, yielding an impressive objective response rate of 30% and a disease control rate of 70%."

Douglas Loe, an analyst with Echelon Wealth Partners, provided an update on this biotech's platform pipeline targeting ovarian and blood cancers, as well as respiratory syncytial virus.
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André Uddin, Mackie Research Capital (11/21/17)
"Immunovaccines Inc. announced it is expanding its collaboration with Leidos to develop a DepoVax-based malaria vaccine candidate. We are maintaining our SPECULATIVE BUY rating and target price of $2.20. . .following the achievement of several preclinical milestones, Leidos and the U.S. Agency for International Development selected IMV's DepoVax platform as one of the preferred formulations to further develop a preventative, peptide-based malaria vaccine candidate. . .Leidos and USAID made this decision as IMV's DepoVax-formulated vaccine candidates demonstrated immune protection against the malaria parasite delivered by mosquito bites in prior studies."

Douglas Loe, Echelon Wealth Partners (11/21/17)
"Immunovaccine Inc. provided a pipeline update this morning, with yet another example of how its lipid-based, water-free DepoVax platform can engender antigen-specific B-cell and T-cell immune response, in this case in malaria in partnership with VA-based conglomerate Leidos. . .the key takeaway today is that the partnership generated sufficiently positive preclinical data to justify, in Leidos' view, advancing into formal clinical testing. We assume that Leidos will assume most clinical costs other than production of DepoVax, so forthcoming malaria clinical studies do not materially impact our near-term EBITDA or cash flow projections that remain more focused on DPX-Survivac and DPX-RSV."

More Expert Comments

Experts Following This Company

Endri Leno, Equity Analyst – National Bank of Canada
Douglas Loe, Analyst – Echelon Wealth Partners
Jason McCarthy, Analyst – Maxim Group
André Uddin – Mackie Research Capital

The information provided above is from analysts, newsletters, the company and other contributors.

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Investing Highlights
Unique Delivery Platform
Unique target (survivin) in Immuno-Oncology for T Cell activation
Multiple clinical milestones between now and the end of 2018
catalyst Calendar