ProMIS Neurosciences Inc. (PMN:TSX; ARFXF:OTCQB) partnered with BC Neuroimmunology Lab (BCNL) to develop and offer highly accurate, objective tests for Alzheimer's disease detection, diagnosis and monitoring, it announced in a news release.
"We now have blood-based biomarkers that can provide the information necessary to detect Alzheimer's disease, including pre-symptomatic disease. Measurable Alzheimer's neuropathology precedes cognitive decline by 15-20 years, and this represents an invaluable window of opportunity for prevention, and prevention begins with detection. ProMIS' ultimate mission with its partner BCNI is to build a portfolio of assays that enables early detection and monitoring of disease progression before symptoms arise," ProMIS Executive Chairman Eugene Williams said in the release.
In that regard, ProMIS and BCNL formed a revenue-sharing joint venture. These collaborators intend to start by offering blood-based assays for the two brain protein biomarkers, neurofilament light chain (NfL) and phosphorylated tau181 (P-tau181).
"The progress this year in measuring P-tau181 in the blood marks an inflection point in the fight against Alzheimer's disease," added Williams.
"We know that lifestyle interventions like diet, exercise and mental stimulation can have a significant impact on progression to cognitive decline," said Dr. Sharon Cohen, director of the Toronto Memory Program. "What has been missing prior to the recent advent of blood-based biomarkers is a convenient and accurate way to measure the impact of these interventions in pre-symptomatic patients. ProMIS' exciting work with blood-based biomarkers for the detection and monitoring of AD could potentially contribute to a breakthrough in how we work with our patients to prevent Alzheimer's disease."
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